Waupaca is a city in and the county seat of Waupaca County in the state of Wisconsin, United States. The population was 6,069 at the 2010 census. The city is believed to be named after Sam Waupaca (or Chief Wapuka) of the Potowatomi tribe.
The city is located mostly within the Town of Waupaca, and it is politically independent of the town. A portion extends west into the adjacent Town of Farmington, and there is also a noncontiguous area of the city in the Town of Lind to the south. The city is divided into natural areas, city areas, and industrial areas.