Kirkwood is a farming town and census-designated place located in Colerain Township, Lancaster County, Pennsylvania, United States, in the Lancaster Metro area, in Pennsylvania Dutch Country, near the Chester County border. The zip code is 17536. As of the 2010 census the population was 396.
The post office in Kirkwood was established in 1856.
Kirkwood is home to the trucking company Lester M Prange.