New Burnside is a village in Johnson County, Illinois, United States. The population was 211 at the 2010 census.
In 1878, New Burnside peaked in population at 1,200 when the railroad ran through the middle of the town. The population decreased gradually after the railroad was abandoned. More recently, the Tunnel Hill State Trail for bicycles was built along the abandoned line. The village was founded in 1872, and was a Cairo and Vincennes Railroad boom-town. Much of its founding was based on the same coal mining industry that grew Harrisburg and Carrier Mills, but slowly turned to an orchard-based economy by 1900. It was named after Civil War general Ambrose Burnside.