Island Grove is an unincorporated community in Alachua County, Florida, United States. Its ZIP code is 32654.
Island Grove can be found near the southeastern terminus of County Road 325 and US 301. The CSX Wildwood Subdivision also passes through the community.
Residents of Island Grove are zoned for their children to attend Chester Shell Elementary School and Hawthorne JR/SR High, both in Hawthorne, Florida.