Vance is a town in Tuscaloosa and Bibb counties in the U.S. state of Alabama. As of the 2010 census it had a population of 1,529. It is most famous for the Mercedes-Benz U.S. International plant, currently the only one in North America. The current mayor of Vance is Keith Mahaffey.
The Tuscaloosa County portion of Vance is part of the Tuscaloosa Metropolitan Statistical Area, while the Bibb County portion is part of the Birmingham–Hoover Metropolitan Statistical Area.