Stoneville is an unincorporated community located in northeastern Washington County, Mississippi. Deer Creek flows through Stoneville.
A post office was established in 1876, and remains open. Stoneville was incorporated in 1882, though it is no longer incorporated.
Stoneville was a stop on the Yazoo and Mississippi Valley Railroad, established in the 1880s, and a stop on the Columbus and Greenville Railway, established in the 1920s.
The Jamie Whitten Delta States Research Center is located in Stoneville. George B. Vogt was a notable entomologist there.