New Pine Creek is a census-designated place and unincorporated community in Lake County, Oregon, United States. Although it is unincorporated, it has a post office with a ZIP code of 97635. New Pine Creek lies on U.S. Route 395 at the Oregon–California border, just north of New Pine Creek, California, and east of Goose Lake.
West of town is the Goose Lake State Recreation Area, along Stateline Road near the lake. The north–south running Lake County Railroad passes near the recreation area. East of town is the Fremont National Forest.
Thought to be Lake County's oldest settlement, New Pine Creek was originally to be named Pine Creek after a nearby stream. However, since another community was already using that name, postal authorities preferred an alternative. The New Pine Creek post office opened in 1876. S. A. Hamersley was the first postmaster.
New Pine Creek is the southernmost settlement in the state of Oregon.