Lusk is a high-plains town in the eastern part of the state of Wyoming. The town is the seat of Niobrara County. The town was founded in July 1886, by Frank S. Lusk, a renowned Wyoming rancher, partner in the Western Live Stock Company, and stockholder in the Wyoming Central Railway. Cattle ranching remains the primary industry in the town of Lusk.
The population was 1,567 at the 2010 census. The town of Lusk is known for being the county seat of the least populated county in the least populated state in the US. In comparison, the county is approximately twice the size of the state of Rhode Island, with only 1/500 of the population.