Sayre is the largest borough in Bradford County, Pennsylvania, 18 miles (29 km) southeast of Elmira, New York. In the past, various iron products were made there. In 1900, 5,243 people lived there; in 1910, 6,426 people lived there, and in 1940, 7,569 persons made their homes in Sayre. The population was 5,587 at the 2010 census.
Sayre is part of the Penn-York Valley ("The Valley"), a group of four contiguous communities in New York and Pennsylvania: Waverly, New York; South Waverly, Pennsylvania; Sayre; Athens, Pennsylvania, and smaller surrounding communities with a combined population near 35,000. Sayre is the principal city of the Sayre, PA Micropolitan Statistical Area.