La Pine is a city in Deschutes County, Oregon, United States, incorporated on December 7, 2006.
La Pine is part of the Bend, Oregon Metropolitan Statistical Area. The population was 1,653 at the 2010 census. La Pine is in an isolated area of Central Oregon, consisting of a loose collection of homes and businesses along U.S. Highway 97 about 30 miles (48 km) southwest of Bend. Most of the residential development is concealed from the highway itself. Several peaks of the Cascade Range are prominently visible from the community.
La Pine is in the valley of the Little Deschutes River, a tributary of the Deschutes River. The river provides recreational opportunities such as fishing, swimming, canoeing and other leisure activities.