Stephens College is a women's college located in Columbia, Missouri. It is the second oldest female educational establishment that is still a women's college in the United States. It was founded on August 24, 1833 as the Columbia Female Academy. In 1856, David H. Hickman turned it into a college, The Columbia Female Baptist Academy. In the late 19th century it was renamed Stephens Female College after James L. Stephens endowed the college with $20,000. The campus includes a National Historic District: Stephens College South Campus Historic District.

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