Blakeslee is an unincorporated community in Tobyhanna Township in Monroe County, Pennsylvania, United States. Blakeslee is located at the intersection of Pennsylvania Route 115 and Pennsylvania Route 940.
A post office was established in Blakeslee in 1884 and named after Jacob Blakeslee, the first postmaster. The post office was located near Burger Road near his 300-acre homestead. Jacob Blakeslee would later serve as justice of the peace for the small community. The Blakeslee United Methodist Church was established in 1897.