Texas Southern University (shortened to Texas Southern or simply TSU) is a historically black university (HBCU) located in Houston, Texas, United States, accredited by the Southern Association of Colleges and Schools.

The University was established in 1927 as the Houston Colored Junior College, through its private college phase as Houston Colored College. On March 3, 1947, the state declared this to be the first state university in Houston and it was renamed Texas State University for Negroes. In 1951, the name changed to Texas Southern University.

Texas Southern University is one of the largest and most comprehensive HBCUs in the nation and one of only four independent public universities in Texas (those not affiliated with any of Texas' six public university systems). TSU is the only HBCU in Texas recognized as one of America's Top Colleges by Forbes. TSU is also recognized as the leading producer of college degrees to African-Americans and Hispanics in Texas and ranks fourth (4th) in the nation in African-American conferred doctoral and professional degrees. The University is a member-school of the Thurgood Marshall College Fund.

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