Nome (/ˈnoʊm/; Inupiaq: Siqnazuaq IPA: [siqnɐzuɑq]) is a city in the Nome Census Area in the Unorganized Borough of the U.S. state of Alaska. The city is located on the southern Seward Peninsula coast on Norton Sound of the Bering Sea. In 2016 the population was estimated at 3,797, a rise from the 3,598 recorded in the 2010 Census, up from 3,505 in 2000. Nome was incorporated on April 9, 1901, and was once the most-populous city in Alaska. Nome lies within the region of the Bering Straits Native Corporation, which is headquartered in Nome.
The city of Nome claims to be home to the world's largest gold pan, although this claim has been disputed by the Canadian city of Quesnel, British Columbia.
In the winter of 1925, a diphtheria epidemic raged among Alaska Natives in the Nome area. Fierce territory-wide blizzard conditions prevented the delivery of a life-saving serum by airplane from Anchorage. A relay of dog sled teams was organized to deliver the serum.