Seminole State College of Florida (commonly referred to as Seminole State) is a public state college located in Sanford, Florida, United States. Seminole State is a member institution of the Florida College System, and competes in National Junior College Athletic Association (NJCAA) Region VIII (Suncoast Conference) in baseball, softball and women's golf.

Founded in 1965, the Florida State Legislature signed a charter creating "Seminole Junior College." The college opened in August 1966 with 700 students, at a former citrus grove in Seminole County, near U.S. Route 17/92 and Interstate 4 (between the cities of Lake Mary and Sanford). By October 1971, Seminole Junior College's enrollment had exceeded 7,000, and by 1975, Seminole Junior College became "Seminole Community College", with enrollment reaching 14,161. In 2006, Seminole Community College partnered with the University of Central Florida to launch "DirectConnect to UCF", which guarantees Seminole Community College (SCC) graduates admission to the university, as well as academic advising by university counselors. In September 2009, the SCC Board of Trustees unanimously approved a motion to rename the institution "Seminole State College of Florida," eight months after the introduction of the institution's first state-approved bachelor's degree program, the Bachelor of Applied Science (B.A.S.) in interior design.

As of 2011, the college serves over 30,000 students, full-time and part-time, and is also one of the largest employers in Seminole County. The college has expanded into four campuses since 1965, all based within Seminole County, Florida. Its main campus is located in Sanford, and its satellite campuses located in Oviedo, Altamonte Springs and Heathrow. The Oviedo campus had opened in 2001, the Heathrow campus opened in 2007, and the Altamonte Springs campus had opened in 2008.

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