Kansas City University of Medicine and Biosciences (KCUMB) is a health sciences university located in Kansas City, in the U.S. state of Missouri. The university was founded in 1916, and currently consists of both a College of Osteopathic Medicine and a College of Biosciences. The school occupies the original site of Children’s Mercy Hospital.

KCUMB is accredited by the Higher Learning Commission of the North Central Association of Colleges and Schools and recognized by the Coordinating Board of Higher Education for the Missouri Department of Higher Education. The College of Osteopathic Medicine is accredited by the American Osteopathic Association's Commission on Osteopathic College Accreditation.

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