Wedowee is a town in Randolph County, Alabama, United States. At the 2010 census the population was 823, up from 818 in 2000. The small town is the county seat of Randolph County. It was initially incorporated in 1836, but its charter lapsed by the late 19th century. It was reincorporated in 1901.
Randolph County High School is located in Wedowee.