Tanana /ˈtænənɑː/ (Hohudodetlaatl Denh in Koyukon) is a city in the Yukon-Koyukuk Census Area in the U.S. state of Alaska. At the 2010 census the population was 246, down from 308 in 2000. It was formerly known as Clachotin, adopted by Canadian French.
Jules Jetté (1864–1927), a Jesuit missionary who worked in the area and documented the language, recorded the Koyukon Athabascan name for the village as Hohudodetlaatl Denh, literally, ‘where the area has been chopped’. Several residents are chronicled in the 2012 Discovery Channel TV series Yukon Men. Almost 80% of the town's population are Native Americans, traditionally Koyukon (Denaakk'e) speakers of the large Athabaskan (Dené) language family.