Prescott is a city and the county seat of Nevada County, Arkansas, United States. The community had a population of 3,868 at the 2000 census. Prescott is part of the Hope Micropolitan Statistical Area.
Located 100 miles southwest of Little Rock, Prescott was developed on the Prairie D'Âne, named by French colonists before the United States acquired this area. The prairie consisted of approximately 25–30 square miles of rolling open land, surrounded by forest. The area had been a well-known crossroads prior to construction of the Cairo & Fulton Railroad. To the west lies the city of Washington, to the east lies the city of Camden, while to the south lies the Red River, with Shreveport, Texarkana, and Dallas beyond.
As of 2014, Prescott and Nevada County had sixteen properties listed on the National Register of Historic Places. Elkin's Ferry Battleground and the Prairie D'Ane Battlefield are further recognized as National Historic Landmarks within a National Historic Landmark District.