Pomona is an unincorporated community and census-designated place (CDP) in Howell County, Missouri, United States. It is located midway between Willow Springs and West Plains. As of the 2010 census it had a population of 511.
A post office called Pomona has been in operation since 1895. The community was named for Pomona, the Roman goddess of fruit trees; this area was a major producer of apples.