Melstone is a town in far eastern Musselshell County, Montana, United States, along U.S. Route 12. The population was 96 at the 2010 census. The town was established in 1908 as a base for operating crews on the Chicago, Milwaukee, St. Paul and Pacific Railroad, then under construction in Montana. Although the railroad was abandoned in 1980, Melstone survives as a community center for farmers and ranchers in the lower Musselshell River valley. It has a K-12 school with a staff of 16, which in the Fall of 2017 successfully began a 4-day school week.