Manomet is a seaside village of Plymouth, Massachusetts, United States. It is named for the Manomet Native American sub-group of the Wampanoag whose settlement was located atop the dominant hill in the region when European settlers arrived in Plymouth in 1620. Manomet has a Post Office in the business district whose ZIP code is 02345. Residents and businesses in this village that are non-Post Office box holders use Plymouth's ZIP code of 02360.
Pilgrim Station, the only operating nuclear power plant in Massachusetts, is located in Plymouth, north of Manomet.
Manomet is also home to Manomet Center for Conservation Sciences, a global conservation and sustainability nonprofit organization.