Irvine (locally /ˈɜːrvən, ˈɜːrvaɪn/) is a home rule-class city in Estill County, Kentucky, in the United States. It is the seat of its county. Its population was 2,715 at the time of the 2010 census. It is located on the Kentucky River at the junction of Kentucky Route 52 and Kentucky Route 89.
Irvine annually hosts the Mountain Mushroom Festival on the last weekend of April. Irvine and nearby Ravenna are known within Estill County as the "Twin Cities".