Huntsville is a city in Madison County, Arkansas, United States. The population was 2,346 at the 2010 census. The city is the county seat of Madison County, located in the northwest corner of the state. During the American Civil War in 1862, it was the site of what became known as the Huntsville Massacre.
Huntsville is part of the Fayetteville–Springdale–Rogers, AR-MO Metropolitan Statistical Area.