Hammondsville is an unincorporated community in central Saline Township, Jefferson County, Ohio, United States. Although it is unincorporated, it has a post office, with the ZIP code of 43930. It lies along State Route 213. The community is part of the Weirton-Steubenville, WV-OH Metropolitan Statistical Area. Notable residents are Pap "Buckeye" Hogue and Bevo Francis.