Fisty is an unincorporated community in Knott County, Kentucky, United States. Fisty is located at the junction of Kentucky Route 550 and Kentucky Route 721 6.5 miles (10.5 km) west of Hindman. Fisty has a post office with ZIP code 41743.
The name is said to have come from a local who went by "Fisty Sam" Combs. The name is pronounced as if spelled "feisty."